Equipment available


    Biophysical platform

Biophysics / NMR

Molecular structure and interaction analysis using nuclear magnetic resonance (NMR)


NMR fragment screening

A tool combining different biophysical techniques for the discovery of new ligands that modulate protein-protein interactions.


Analytical Ultra-Centrifuge

ProteomeLab XL-1 (Beckman Coulter)


Isothermal titration calorimetry (ITC)

MicroCal iTC200 (Malvern)


SpectroFluorometers

Cary Eclipse Fluorescence Spectrophotometer (Agilent)


Circular Dichroism (CD)

Spectropolarimeter J-810 (Jasco)


Equipment Biophysic

    Other platforms and infrastructures available at the Institute

Histology

Preparation and observation of normal or tumor tissues in order to study their properties

Genomics

Determining the genetic code and measuring gene expression

Flow Cytometry

Sorting and analysis of cell physical and molecular characteristics

Proteomics

Identification and quantification of proteins based on their chemical composition

Bioinformatics

Complex computer analysis of a large volume of data generated by research

Bio-Imaging

State-of-the-art microscopy for research

Drug Discovery Unit

Conception, synthesis and discovery of new drugs

IRIC

    Platforms and infrastructures available outside of IRIC

Structural biology platform at UdeM

Access to different biophysical resources (SEC-MALS, 700 MHz Bruker Avance NEO with cryo-probe, BioSAXS, ITC...)

Biochemistry and Molecular Medicine Department

Access to the Diskovery Flex super-resolution microscope and to the Zeiss Elyra SP.1

QANUC

The Quebec/Eastern Canada High Field NMR Facility (QANUC) provides a 800 MHz Bruker Avance III with a TCI cryoprobe equipped with four channels (1H, 13C, 15N and 2H).

Cryo EM

The Facility for Electron Microscopy Research (FEMR) is a world-class, open access electron microscopy facility at McGill University.

cryoEM

    Software / resources available in the lab

Biomolecular NMR platform

Structure calculations

Molecular visualisation

Structure analysis

NMR-related, NMR diffusion...